Vitamin D: Vitamin D and metabolites are mainly excreted in the bile and faeces. Excess absorbed calcium excreted via urine.

Metabolism: Vitamin D3: Hydroxylated in liver to form 25-hydroxycholecalciferol, then hydroxylated in kidney to form active metabolite 1,25-dihydroxycholecalciferol.Įxcretion: Calcium salt: Unabsorbed calcium mainly excreted via faeces. May be stored in adipose and muscle tissue for prolonged periods. Vitamin D: Vitamin D and metabolites binds to vitamin D -binding protein and are circulated in the blood. Vitamin D3: Well-absorbed from GI tract in the presence of bile.ĭistribution: Calcium: Skeletal tissue, breast milk. It is necessary for the regulation and regulation of calcium and phosphate homoeostasis and bone mineralisation.Ībsorption: Calcium: Approx 33% of oral calcium absorbed via active transport and passive diffusive in small intestine. It is also used as an adjunct in the prevention and treatment of osteoporosis. in stimulating intestinal calcium transport 24 hours after administration. The VITAL, ViDA and D2d randomized clinical trials (combined number of participants >30,000) indicated that vitamin D supplementation of vitamin D-replete adults (baseline serum 25OHD >50. Description: Calcium salt can be used in the prevention and treatment of calcium deficiency states. A major polar metabolite of cholecalciferol (vitamin D3) obtained from chick.

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